Teacher 各学科教員紹介

専門分野・研究テーマ

【専門分野】

薬理学

【研究テーマ】

薬物依存、神経障害性疼痛

著書・論文等

【書籍】

1. Kiguchi N, Matsuzaki S, Saika F, Kobayashi D and Kishioka S: Epigenetic regulation of peripheral macrophages in neuropathic pain. (Book) Chapter 2, Epigenetics of Chronic Pain, Vol 9, 49-67 (2019)
2. 岸岡史郎：オピオイド、鎮痛および疼痛管理　p.569 - 623　グッドマン・ギルマン　薬理書［上］薬物治療の基礎と臨床（分担訳者）第13版　橋本敬太郎、赤池昭紀、石井邦雄、川西　徹　監訳　広川書店 (2022)

【論文】

1. Kiguchi N, Sakaguchi H, Kadowaki Y, Saika F, Fukazawa Y, Matsuzaki S and Kishioka S: Peripheral administration of interleukin-13 reverses inflammatory macrophage and tactile allodynia in mice with partial sciatic nerve ligation. J Pharmacol Sci, 133 (1), 53-56 (2017)
2. Saika F, Kiguchi N, Wakida N, Kobayashi D, Fukazawa Y, Matsuzaki S and Kishioka S: Upregulation of CCL7 and CCL2 in reward system mediated through dopamine D1 receptor signaling underlies methamphetamine-induced place preference in mice. Neurosci Lett, 665, 33-37 (2018).
3. Kiguchi N, Kobayashi D, Saika F, Matsuzaki S and Kishioka S: Inhibition of peripheral macrophages by nicotinic acetylcholine receptor agonists suppresses spinal microglial activation and neuropathic pain in mice with peripheral nerve injury. J Neuroinflammation, 15(1), 96 (2018)
4. Ding H, Kiguchi N, Kishioka S, Ma T, Peters CM and Ko MC: Differential mRNA expression of neuroinflammatory modulators in the spinal cord and thalamus of type 2 diabetic monkeys. J Diabetes, (2018)

【講演・口頭発表】

1. 岸岡史郎、木口倫一、松﨑伸介、雑賀史浩 マクロファージにおけるニコチン受容体を介した神経障害性疼痛制御機構 特定研究：ニコチン受容体を標的とした炎症性神経・精神疾患の診断と治療戦略 喫煙財団発表（2019年7月、東京）口演
2. Kiguchi N, Uta D, Uchida H, Matsuzaki S and Kishioka S Contribution of gastrin-releasing peptide-expressing neurons in the spinal dorsal horn to pathological itch. 第42回日本神経科学・第62回日本神経化学 合同大会　Neuro2019（2019年7月、新潟）口演
3. Kiguchi N, Matsuzaki S and Kishioka S Roles of itch-responsive GRP receptor-expressing neurons in the spinal dorsal horn 第48回内藤カンファレンス（2019年10月、札幌）口演
4. Kishioka S, Saika F and Kiguchi N Peripheral administration of a4b2 nAChR agonist ameliorates neuropathic pain elicited by type 2 diabetes mellitus in mice.
   Novel Pain Therapeutics: From Basic Research to Clinical Translation and Rehabilitation（2019年10月、Rende；University of Calabria, Italy）口演